0725 TIME COURSE FOR PHENOCONVERSION TO A DEFINED NEURODEGENERATIVE DISEASE IN WOMEN WITH IDIOPATHIC REM SLEEP BEHAVIOR DISORDER WITH AND WITHOUT ANTIDEPRESSANT USE
نویسندگان
چکیده
منابع مشابه
Sleepiness in Idiopathic REM Sleep Behavior Disorder and Parkinson Disease.
OBJECTIVE To determine whether patients with idiopathic and symptomatic RBD were sleepier than controls, and if sleepiness in idiopathic RBD predicted earlier conversion to Parkinson disease. METHODS The Epworth Sleepiness Scale (ESS) and its determinants were compared at the time of a video-polysomnography for an RBD diagnosis in patients with idiopathic RBD, in patients with Parkinson disea...
متن کاملQuantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder.
OBJECTIVE Idiopathic REM sleep behavior disorder (RBD) is a potential preclinical marker for the development of neurodegenerative diseases, particularly Parkinson disease (PD) and Lewy body dementia. However, the long-term risk of developing neurodegeneration in patients with idiopathic RBD has not been established. Obtaining an accurate picture of this risk is essential for counseling patients...
متن کاملNeurodegenerative Disorder Risk in Idiopathic REM Sleep Behavior Disorder: Study in 174 Patients
OBJECTIVE To estimate the risk for developing a defined neurodegenerative syndrome in a large cohort of idiopathic REM sleep behavior disorder (IRBD) patients with long follow-up. METHODS Using the Kaplan-Meier method, we estimated the disease-free survival rate from defined neurodegenerative syndromes in all the consecutive IRBD patients diagnosed and followed-up in our tertiary referal slee...
متن کاملREM sleep behavior disorder and REM sleep without atonia in patients with progressive supranuclear palsy.
STUDY OBJECTIVE To compare sleep characteristics, rapid eye movement (REM) sleep without atonia, and REM sleep behavior disorder (RBD) in patients with progressive supranuclear palsy (tauopathy), patients with Parkinson's disease (a synucleinopathy), and control subjects. DESIGN Sleep interview, overnight polysomnography, and Multiple Sleep Latency Tests. PATIENTS Forty-five age- and sex-ma...
متن کاملSleep stability and transitions in patients with idiopathic REM sleep behavior disorder and patients with Parkinson's disease.
OBJECTIVE Patients with idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) are at high risk of developing Parkinson's disease (PD). As wake/sleep-regulation is thought to involve neurons located in the brainstem and hypothalamic areas, we hypothesize that the neurodegeneration in iRBD/PD is likely to affect wake/sleep and REM/non-REM (NREM) sleep transitions. METHODS We determ...
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ژورنال
عنوان ژورنال: Sleep
سال: 2017
ISSN: 0161-8105,1550-9109
DOI: 10.1093/sleepj/zsx050.724